Brody Environmental Center

Abstracts

A wide variety of research is done at the Brody Environmental Center. The following are some of the abstracts that have been done concerning the research conducted at the BEC.

1993 Midwest J. Anim. Sci. Vol. 71, Suppl. 1/1993:

Regional changes in skin temperature of immature pigs during long-term exposure to different ambient temperatures. Donald E. Spiers* and B. Ann Becker. p.42

The effects of diets formulated on an ideal protein basis on growth performance and thermal balance of finishing gilts housed in a hot environment. J. Lopez, R. D. Goodband, G. W. Jesse, J. L. Nelssen, M. D. Tokach, D. Spiers and B. A. Becker. p.61

The effects of diets formulated on an ideal protein basis on carcass characteristics and accretion rates of finishing gilts housed in a hot diurnal environment. J. Lopez, R. D. Goodband, G. W. Jesse, J. L. Nelssen, M. D. Tokach, D. Spiers and B. A. Becker. p.61

1993 ASAS J. Anim. Sci. Vol. 71, Suppl. 1/1993: Thermal responses of cattle to ergovaline during long-term exposure to cold stress. Q. Zhang*, D. E. Spiers, A. Al-Haidary, G. E. Rottinghaus and G. B. Garner. p. 114

Fescue toxicosis: The environmental stress connection. D. E. Spiers. p.116

1994 Midwest J. Anim. Sci. Vol. 72, Suppl. 2/1994: Relationship between ambient temperature and acute thermoregulatory response of rats to ergovaline. Q. Zhang, D. E. Spiers*, A. Al-Haidary, G. E. Rottinghaus and G. B. Garner. p. 43

Effect of nicotinic acid supplementation on heat stress responses to prepuberal female rats. A. DiCostanzo, D. E. Spiers and J. N. Spain. p. 161

1994 ASAS: J. Anim. Sci. Vol. 72, Suppl. 1/J. Dairy Sci. Vol. 77, Suppl. 1/1994

Modification of thermoregulatory ability in the rat following long-term heat exposure. M. Nesbitt*, D. E. Spiers. p. 154

Circadian rhythm of core body temperature in beef calves under cold and heat stress conditions. Q. Zhang, D. E. Spiers*, A. Al-Haidary, G. E. Rottinghaus, G. B. Garner. p. 154

Shifts in thermoregulatory ability of beef calves following intake of endophyte-infected tall fescue during heat stress. A. Al-Haidary*, D. E. Spiers, Q. Zhang, G. E. Rottinghaus, G. B. Garner. p. 155

Nicotinic acid supplementation in lactating Holstein cows during the summer. A. DiCostanzo, J. N. Spain and D. E. Spiers. p. 186

1995 Midwest J. Anim. Sci. Vol. 73, Suppl. 1/1995:

40 Thermoregulatory responses of heat-stressed rats to repeat-administration of endophyte-infected tall fescue toxin. M. D. Nesbitt*, P. A. Eichen, D. E. Spiers, G. E. Rottinghaus and G. B. Garner. p. 49

1995 ASAS: J. Anim. Sci. 1995 73 Suppl. 1

Effect of administration of ergovaline on the thermoregulatory functions of beef calves under heat stress. A. Al-Haidary*, D. E. Spiers, G. E. Rottinghaus and G. B. Garner. p. 132

Thermoregulatory responses of preweanling and adult rats to ergotamine under heat stress and thermoneutral conditions. M. D. Nesbitt* and D. E. Spiers. p. 132

Effect of restricted energy intake during long-term exposure to heat on growth and thermoregulation of rats. A. P. Mtukuso*, D. E. Spiers and P. A. Eichen. p. 141

Recombinant bovine somatotropin stimulation of growth in prepubertal rats at different ambient temperatures. D. E. Spiers*, P. A. Eichen, R. L. Matteri and J. C. Byatt. p. 150

1996 ASAS: J. Anim. Sci. 1996 74 Suppl. 1

Recombinant bovine placental lactogen stimulation of growth in adult rats at different ambient temperatures. D. E. Spiers*, P. A. Eichen, E. L. Robinson, R. L. Matteri and J. C. Byatt. p. 154

Recombinant bovine placental lactogen stimulation of growth in prepubertal rats at different ambient temperatures. P. A. Eichen*, D. E. Spiers, E. L. Robinson, R. L. Matteri and J. C. Byatt. p. 155

1997 ASAS: J. Anim. Sci. 1997 75 Suppl. 1

Recombinant bovine prolactin effects in prepubertal and adult rats at different ambient temperatures. P. A. Eichen*, D. E. Spiers, K. E. Westhoff and J. C. Byatt. p. 158

Potential benefit of an anthelmintic in reducing hyperthermia associated with fescue toxicosis. D. E. Spiers*, B. L. Snyder, P. A. Eichen, G. E. Rottinghaus and G. B. Garner. p. 212

1998 ASAS: J. Anim. Sci. Vol. 76, Suppl. 1/J. Dairy Sci. Vol. 81, Suppl. 1/1998

Effects of recombinant growth promotants on lactating rats maintained at different ambient temperatures. P. A. Eichen*, D. E. Spiers, K. E. Westhoff, J. C. Byatt and A. Gertler. p. 95

Determination of sensitivity to endophyte-infected tall fescue for beef heifers in a controlled environment. B. L. Snyder, D. E. Spiers, E. J. Scholljegerdes, S. VanDyke, G. E. Rottinghaus and E. L. Piper. p. 97

Strategic night cooling of dairy cows during heat challenge reduces impact on thermal status. D. E. Spiers*, J. N. Spain and B. L. Snyder. p. 103

The relationship between students' learning styles and teaching performance in an introductory animal science course. B. L. Garton, J. N. Spain, W. E. Trout, D. E. Spiers and W. R. Lamberson*. p. 1443

1999 ASAS: J. Anim. Sci. Vol. 77, Suppl. 1

Preliminary study of dairy cow response to ergotized barley during heat stress. H. Al-Tamimi*, D. Spiers, J. Spain, G. Rottinghaus, N. Hill, D. Chatman, J. Underwood and M. Ellersieck. p. 146

A chronic rat model of performance and thermoregulatory responses to endophyte-infected tall fescue diet. P. A. Eichen, D. E. Spiers, G. Rottinghaus and K. Fritsche. p. 147

2000 Midwest: J. Anim. Sci. Vol. 78, Suppl. 2

A chronic model of performance and thermoregulatory responses to ergot bodies. P. A. Eichen*, D. E. Spiers, G. Rottinghaus and K. Fritsche. p. 37

Assessment of feedlot cattle responses to heat stress using continuous monitoring methods. M. J. Leonard*, D. E. Spiers and G. L. Hahn. p. 37

2000 ASAS: J. Anim. Sci. Vol. 78, Suppl. 1/J. Dairy Sci. Vol.83, Suppl. 1/2000

Physiological responses of steers exposed to repeated sinusoidal heat challenge. M. J. Leonard*, D. E. Spiers, G. L. Hahn, K. J. Imhoff and L. E. McVicker. p. 44

A model of fescue toxicosis: effect of exposure time to endophyte-infected diet. P. A. Eichen*, M. S. Eibs, D. E. Spiers, G. Rottinghaus and K. Fritsche. p. 45

Nitric oxide effects on rats fed an endophyte-infected seed diet. H. Al-Tamimi *, D. Spiers and M. Ellersieck. p. 46

A field study of dairy cow performance using different fan-cooling strategies. J. D. Sampson*, C. Bowe, J. Denbigh, M. Ellersieck, J. N. Ellersieck, J. N. Spain, D. Spiers and J. Zulovich. p. 232

2001 Midwest: J. Anim. Sci. Vol. 79, Suppl. 2

Effects of summer heat on growth, carcass composition, and quality grades in feedlot steers. M. J. Leonard*, E. P. Berg, D. E. Spiers and L. E. McVicker. p. 52

2001 ASAS: J. Anim. Sci. Vol. 79, Suppl. 1/J. Dairy Sci. Vol. 84, Suppl.1

Utilization of a small animal model of fescue toxicosis to evaluate the potential benefit of Ascophyllum nodosum. P. A. Eichen*, D. E. Spiers, G. Rottinghaus and D. P. Colling. p. 16

Use of Ascophyllum nodosum to reduce problems associated with fescue toxicosis in cattle during heat challenges. M. J. Leonard*, D. E. Spiers, G. Rottinghaus and D. P. Colling. p. 17

The relationship of indicators of thermal balance and milk production of cows on Missouri dairy farms. James Spain*, Julie Sampson and Don Spiers. p. 268

Effects of cooling strategies on physiological responses to heat challenge. K. M. Spurlin, D. E. Spiers, M. Ellersieck and J. N. Spain. p. 278

Evaluation of a model to predict internal body temperature in feedlot cattle during summer heat. L. E. McVicker*, M. J. Leonard and D. E. Spiers. p. 279

2002 ASAS National Meeting Quebec J. Anim. Sci. Vol. 80, Suppl. 1

The effect of environmental stress on the performance of dairy cattle. J.N. Spain*, M. Lucy, and D. Spiers, Brody Environmental Center, University of Missouri - Columbia. 2002

Effects of simultaneous evaluation of cooling strategies on production responses and intake behavior during heat challenge in dairy cattle. K. M. Spurlin*, D. E. Spiers, M. Ellersieck, J. N. Spain, University of Missouri - Columbia. 2002

2002 Kansas City International Biometeorology Conference

The effect of progressively higher level of heat challenge on temperature control of cattle. A. Al-Haidary, M. J. Leonard, D. E. Spiers, King Saud University, Riyadh, Saudi Arabia, and University of Missouri, Columbia, MO.

Evaluation of feedlot cattle response to summer heat in open or shaded pens. L. E. McVicker, M. J. Leonard, D. E. Spiers. Department of Animal Sciences, University of Missouri, Columbia, MO.

Effects of exogenous nitric oxide on thermoregulatory characteristics of cattle experiencing fescue toxicosis during cyclical heat stress. H. Al-Tamimi, D. Spiers, L. Lakritz, M. Ellersieck, G. Rottinghaus. University of Missouri - Columbia, Animal Science Department.

2003 ASAS Midwest Sectional Meeting J. Anim. Sci. Vol. 81, Suppl. 2

Use of Dietary Seaweed Treatment to Reduce Heat Strain in Cattle. L. E. McVicker*, D. E. Spiers, J. E. Williams, K. J. Barnhart, L. N. Thompson, A. Al-Haidary, and D. P. Colling, University of Missouri - Columbia.

Use of Ascophyllum nodosum for alleviation of heat stress in cattle. L. N. Thompson*, J. E. Williams, K. J. Barnhart, L. E. McVicker, D. E. Spiers, and D. P Colling, University of Missouri, Columbia, MO, Acadian Seaplants, Inc.

Miccroarray analysis of gene expression in dominant ovarian follicles (DF) from heat stress (HS) and thermoneutral (TN) heifers. S. J. Kolath*, P. M. Coussens, S. Sipkovsky, S. J. Wilson, D. E. Spiers, J. N. Spain, and M. C. Lucy, University of Missouri, Michigan State University.

Performance of mice divergently selected for sensitivity to fescue toxicosis when challenged with endophyte-infected fescue and heat stress. S. Bhusari1, E. Antoniou1, D. E. Spiers1, W. D. Hohenboken2, P. A. Eichen1, W. R Lamberson1. 1University of Missouri - Columbia, 2Virginia Polytechnic Institute and State University, Blacksburg.

2003 ASAS National Meeting Phoenix J. Anim. Sci. Vol. 81, Suppl. 1

Is iodide responsible for the heat-relief effects of Ascophyllum nodosum? P. A. Eichen*, M. J. Leonard, M. A. Kozma, B. M. Kronk, L. E. McVicker, D. E. Spiers, and D.P Colling, University of Missouri, Columbia, MO, Acadian AgriTech, Kansas City, MO.

Monitoring fescue toxicosis in a pasture environment and evaluating the effect of prior treatment with Ascophyllum nodosum. D. E. Spiers*, L. E. McVicker, J. E. Williams, P. A. Eichen, L. Thompson, G. Rottinghaus, and D. P. Colling, University of Missouri, Columbia, MO, Acadian AgriTech, Kansas City, MO.

2004 Midwest J. Anim. Sci. Vol. 82, Suppl. 2

Effects of fescue toxins and heat stress on gene expression in mouse liver. S. Bhusari, D. E. Spiers, W. R. Lamberson, E. Antoniou, University of Missouri - Columbia.

Relationships between body temperature and performance traits in heat-stressed rats. K. M. Cammack, D. E. Spiers, P. A. Eichen, W. R. Lamberson, University of Missouri.

2004 International Neotyphodium Meeting - Arkansas

Development of a Dose-Response Relationship Between Endophyte-Infected Tall Fescue Seed and Performance of Cattle Exposed to Heat Stress. L. E. Wax, R. A. Madinger, K. K. Radcliff, R. S. Settivari, B. C. Wray, T. J. Evans, G. E. Rottinghaus, D. H. Keisler, and D. E. Spiers. University of Missouri, Columbia, Missouri

2004 ASAS National Meeting - St. Louis J. Anim. Sci. Vol. 82, Suppl. 1

Effectiveness of Ground Endophyte-Infected Tall Fescue Seed in Production of Fescue Toxicosis in Cattle. L. E. Wax, D. E. Spiers, G. E. Rottinghaus, and T. J. Evans. University of Missouri, Columbia, MO

Dose-Response Relationship Between Ergovaline and Physiological Changes Associated with Fescue Toxicosis. P. A. Eichen, D. E. Spiers and G. Rottinghaus, University of Missouri, Columbia, MO

2004 Greece Meeting

Benefit of Dietary Seaweed (Ascophyllum nodosum) in Reducing Heat Strain and Fescue Toxicosis: A Comparative Evaluation. D. E. Spiers, P. A. Eichen, M. J. Leonard, L. E. Wax, G. Rottinghaus, J. E. Williams, D. P. Colling. Animal Science Research Center, University of Missouri, Columbia, USA; Veterinary Diagnostic Laboratory, University of Missouri, Columbia, USA; Acadian AgriTech, Kansas City, USA

2005 FASEB Meeting - San Diego

Effect of Fescue Toxicosis On Hepatic Gene Expression in Mice. S. Bhusari, L.B. Hearne, D. E. Spiers, W. R. Lamberson and E. Antoniou. Dept of Animal Sciences and Statistics, Univ of Missouri-Columbia

2005 ASAS National Meeting - Cincinnati

Is Male Reproduction Affected by Fescue Toxicosis? P. A. Eichen, T. J. Evans, B. C. Wray, L. E. Wax, L. T. King, E. M. Walters, J. K. Critser, G. E. Rottinghaus, and D. E. Spiers, University of Missouri, Columbia.

Does Reduced Caloric Intake Contribute to Symptoms Associate With Fescue Toxicosis? L. E. Wax, P. A. Eichen, G. E. Rottinghaus, and D. E. Spiers, University of Missouri, Columbia.

A Model of Fescue Toxicosis: Responses of Rats to Intake of Endophyte-Infected Tall Fescue. Spiers, D.E., P.A. Eichen, and G.E. Rottinghaus. J. Anim. Sci.. 83: 1423.

Analyses of Thermoregulatory Responses of Feeder Cattle Exposed to Simulated Heat Waves. Brown-Brandl, T.M., R.A. Eigenberg, G.L. Hahn, J.A. Nienaber, T.L. Mader, D.E. Spiers, and A.M. Parkhurst. Int. J. Biometeorol. 49: 285.

2006 Meetings

Parital Reduction of Fescue Toxicosis During Heat Stress Using a Supplemental Yeast Cell Wall Polymer. R. M. Heilman, P. A. Eichen, L. E. Wax, T. Bramble, G. E. Rottinghaus, and D. E. Spiers, University of Missouri, Columbia, Alltech Inc., Nicholasville, KY.

Effect of Fescue Toxicosis on Hepatic Gene Expression. Bhusari, S., L.B. Hearne, D.E. Spiers, W.R. Lamberson, and E. Antoniou. J. Anim. Sci. 84: 1600.

Genomic Analysis of the Impact of Fescue Toxicosis on Hepatic Function. Settivari, R.S., S. Bhusari, T. Evans, P.A. Eichen, L.B. Hearne, E. Antoniou, and D.E. Spiers. J. Anim. Sci. 84: 1279.

Temperature Influences Upon Vascular Dynamics as Measured by Doppler Ultrasonography. B.H. Kirch, G. E. Aiken, and D. E. Spiers. J. Anim. Sci. 84 (Suppl.1):212.

Effect of Feeding Whole Soybeans on Hepatic Gene Expression in Lactating Dairy Cows. J.D. Sampson, R. P. Rhoads, R. J. Tempelman, S. S. Sipkovsky, P. M. Coussens, M. C. Lucy, J. N. Spain, and D. E. Spiers. J. Anim. Sci. 84 (Suppl.1):71.

Effect of Feeding Whole Soybeans on Thermal Balance and Fatty Acid Profiles on Early Lactation Cows During Heat Stress. J.D. Sampson, D. E. Spiers, and J. N. Spain. J. Anim. Sci. 84 (Suppl. 1):68.

Regional Differences in Sweat Rate Response of Steers to Short-Term Heat Stress. D.E. Spiers, L. E. Wax, B. Scharf, and G. E. Aiken. J. Anim. Sci. 84 (Suppl.1):303.

Physiological Responses to Heat Stress in Steers Following Ruminal Administration of Ground Endophyte-Infected Tall Fescue Seed. L.E. Wax, G. Rottinghaus, and D. E. Spiers. J. Anim. Sci. 84 (Suppl.1):75.

The Added Effects of Heat Stress on Alterations in Murine Hepatic Gene Expression Associated with Fescue Toxicosis. S. Bhusari, L. B. Hearne, D. E. Spiers, W. R. Lamberson and E. Antoniou. The Toxicologist 90 (1): 287.

Effect of Fescue Toxicosis on Hepatic Gene Expression. R.S. Settivari,T. Evans, E. Antoniou, C.S. Reddy, and D.E. Spiers. The Toxicologist 90 (1): 287.

2007 Meetings

Effect of FescueToxicosis and Acute Heat Stress on Hepatic Oxidative Activities. Settivari, R. S., T. Evans, E. Antoniou, M. Sutovsky, P. Sutovsky, and D.E. Spiers. The Toxicologist, 96 (1). p. 36.

Feeding Programs That Meet the Challenges of Heat Stress. Spain, J.N. and D.E. Spiers. J. Anim. Sci. Vol. 85, Suppl. 1. p. 623.

Development of a Feed-Restriction Model to Identify Factors Responsible for Fescue Toxicosis-Induced Reduction in Food Intake. Raney, S., P.A. Eichen, and D.E. Spiers. J. Anim. Sci. Vol. 85, Suppl. 1. p. 464.

Adaptation of Angus Steers to Long-Term Heat Stress in the Field Using Controlled Heat Challenge. Scharf, B., L. E. Wax, D. H. Keisler, and D. E. Spiers. J. Anim. Sci. Vol. 85, Suppl. 1. p. 466.

Evaluation of Physiological Differences in Heat Tolerant (Romosinuano) and Heat Susceptible (Angus) Bos taurus Cattle During Controlled Heat Challenge. Scharf, B., L. E. Wax, J. A. Carroll, D. G. Riley, C. C. Chase Jr., S. W. Coleman, D. H. Keisler, and D. E. Spiers, J. Anim. Sci. Vol. 85, Suppl. 1. p. 466.

Thermal Status for Different Breeds of Dairy Cattle Exposed to Summer Heat Sress in a Grazing Environment. Spain, J.N., L. Parsons, R. Crawford, C. Brown, and D. E. Spiers. J. Anim. Sci. Vol. 85, Suppl. 1. p. 540.

Gene Regulation in Liver of Cattle Exposed to Heat Stress. Antoniou, E., E., J. Robertson, and D. Spiers. J. Anim. Sci. Vol. 85, Suppl. 1. p. 625.

The Influence of Temperature Variation Upon Vascular Dynamics in Cattle as Measured by Doppler-Image Ultrasonography. Kirch, B.H., G.E. Aiken, and D.E. Spiers. In A.J. Popay and E.R. Thom (Eds.), Proceedings of the 6th International Symposium on Fungal Endophytes of Grasses, Grassland Research and Practice Series No. 13 (pp. 391-393). Christchurch: New Zealand Grassland Association.

Development of a Feed-Intake Model for Evaluation of Toxins Associated with Endophyte-Infected Fescue. Eichen, P.A., S.L. Raney, G.E. Rottinghaus, and D.E. Spiers. In A.J. Popay and E.R. Thom (Eds.), Proceedings of the 6th International Symposium on Fungal Endophytes of Grasses, Grassland Research and Practice Series No. 13 (pp. 403-405). Christchurch: New Zealand Grassland Association.

Development of a Bovine Model to Evaluate Administration Routines for Endophyte-Infected Tall Fescue. Wax, L.E., G.E. Rottinghaus, and D.E. Spiers. In A.J. Popay and E.R. Thom (Eds.), Proceedings of the 6th International Symposium on Fungal Endophytes of Grasses, Grassland Research and Practice Series No. 13 (pp. 407-409). Christchurch: New Zealand Grassland Association.

Various

M. S. Gadberry, T. M. Denard, D. E. Spiers, and E. L. Piper. Effects of feeding ergovaline on lamb performance in a heat stress environment. J. Anim Sci. 2003 81: 1538-1545.

T. L. Mader, S. M. Holt, G. L. Hahn, M. S. Davis, and D. E. Spiers. Feeding strategies for managing heat load in feedlot cattle. J. Anim Sci. 2002 80: 2373-2382.

A. Al-Haidary, D. E. Spiers, G. E. Rottinghaus, G. B. Garner, and M. R. Ellersieck. Thermoregulatory ability of beef heifers following intake of endophyte-infected tall fescue during controlled heat challenge. J. Anim Sci. 2001 79: 1780-1788.

D. E. Spiers, Q. Zhang, P. A. Eichen, G. E. Rottinghaus, G. B. Garner, and M. R. Ellersieck. Temperature-dependent responses of rats to ergovaline derived from endophyte-infected tall fescue. J. Anim Sci. 1995 73: 1954-1961.

J. Lakritz, M. Leonard, P. Eichen, G. Rottinghaus, D. Spiers. 2001. Whole blood GSH in cattle exposed to heat stress or heat stress plus fescue toxins (E+). 15th Annual Meeting of Central States Soc. Tox., Kansas Cirty, KS, June.

D.E. Spiers, M. J. Leonard, G. L. Hahn, T. L Mader. 2001. Use of telemetry to evaluate the impact of summer heat stress on core body temperature of cattle. Proc. Aust. Physiol. Pharm. 32(2), Suppl. 1: 150P.

D. E. Spiers, P. A. Eichen, M. J. Leonard, L. E. Wax, G. E. Rottinghaus, J. E. Williams, D. P. Colling. Benefit of dietary seaweed (Ascophyllum nodosum) extract in reducing heat strain and fescue toxicosis: a comparative evaluation. Journal of Thermal Biology. 2004. 29:753-757.

D. E. Spiers, J. N. Spain, J. D. Sampson, R. P. Rhoades. Use of physiological parameters to predict milk yield and feed intake in heat-stressed dairy cow. Journal of Thermal Biology. 2004. 29:759-764.

D. E. Spiers, P. A. Eichen, G. E. Rottinghaus. A model of fescue toxicosis: Responses of rats to intake of endophyte-infected tall fescue. J. Anim. Sci. 2005. 83: 1423-1434.

S. Bhusari, L. B. Hearne, D. E. Spiers, W. R. Lamberson, E. Antoniou. 2005. Effect of fescue toxicosis on hepatic gene expression in mice. Division of Animal Sciences1 and Department of Statistics2. University of Missouri-Columbia, Columbia, MO 65211.

K.M. Cammack, D.E. Spiers, P.A. Eichen and W.R. Lamberson. 2005. Relationships between body temperature and performance traits in heat-stressed rats. J. Thermal Biol. 30: 467-477.

S. Bhusari, Z. Liu, L. B. Hearne, D. E. Spiers, W. R. Lamberson and E. Antoniou. 2007. Expression Profiling of Heat Stress Effects on Mice Fed Ergot Alkaloids. Vol. 95 (1): 89-97. Toxicological Sciences.

R.S. Settivari, J.N. Spain, M,R, Ellersieck, J.C. Byatt, R.J. Collier, and D.E. Spiers. 2007. Relationship of thermal status to productivity in heat-stressed dairy cows given recombinant bovine somatotropin. J. Dairy Sci. 90: 1265-1280.

R.S. Settivari, S. Bhusari, T. Evans, P.A. Eichen, L.B. Hearne, E. Antoniou, and D.E. Spiers. 2006. Genomic analysis of the impact of fescue toxicosis on hepatic function. J. Anim. Sci. 84: 1279-1294.

S. Bhusari, L. B. Hearne, D. E. Spiers, W. R. Lamberson, and E. Antoniou. 2007. Transcriptional Profiling of Mouse Liver in Response to Chronic Heat Stress. J. Thermal Biol. (Submitted).

R.S. Settivari, T.J. Evans, P.A. Eichen, G.E. Rottinghaus, and D..E. Spiers. 2007. Short- and long-term responses to fescue toxicosis at thermoneutrality or during heat stress. J. Thermal Biol. (Submitted).

R.S. Settivari, T. J. Evans, E. Rucker, G.E. Rottinghaus, and D.E. Spiers. 2007. Effect of ergot alkaloids associated with fescue toxicosis on hepatic cytochrome P450 and antioxidant proteins. Toxicology and Applied Pharmacology. (Submitted).

Thesis

Sachin Bushari: (Ph.D., Animal Sciences) graduated in Fall 2006; Effects of fescue toxicosis and heat stress on murine hepatic gene expression.

Raja Settivari: (Ph.D., Animal Sciences) graduated in Fall 2007; Temporal effects of fescue toxicosis and heat stress on rat physiology and hepatic gene expression.

The Future

Future research interactions will allow for the determination of:

• relationships between the environment and animal performance

• the effects of environmental toxins and procedures for relief

• critical endpoints for production, reproduction and immune functions affected by environmental stress

• animal or species sensitivity to environmental stressors and development of:

• genetic markers that identify environmental stress in livestock

• strategies for stress relief that contribute to animal health and well-being

• nutritional regimes to produce efficient growth and development in different environment

BEC Goals

Create:

• Biosensor technology that allow for real-time assessment of health status for domestic animals

• Integrated systems that utilize animals thermal balance, ambient conditions, and predicted weather patterns to operate animal comfort systems

• Animal management and comfort systems that reduce environmental stress to enhance animal health and performance

• Understanding of changes in animal gene expression associated with environmental stress

• Scientists who will develop practical solutions for long-term problems of climate change that are associated with global warming and air quality

Read the Article

Today's Challenges

Annual impact of environment on health and general well-being of animals in agriculture totals is at least $8 billion.

Summer heat stress reduces milk production rate and reproductive efficiency of dairy cows to produce an annual loss of $5-6 billion.

More than 22 million acres of fescue produced for over 7 million cattle are infected with a fungus. Consumption of infected fescue and exposure to heat stress produces reproductive losses and reduced weight gain that results in a $600 million annual loss to beef cattle producers.

Heat stress depressed profitability of swine production, with reduced feed intake, growth rate, lean tissue accretion, lactation.

Learn More