Animal Science Faculty

Michael F. Smith

Michael F. Smith


Professor

Reproductive Physiology


160A Animal Science Research Center
Division Of Animal Sciences
Columbia, MO 65211 Michael F. Smith joined the Division of Animal Sciences at the University of Missouri in 1980 where he has a 60% research and 40% teaching appointment. He was a visiting scientist at the Babraham Institute (Cambridge, England; 1987-1987) and the Roslin Institute (Edinburgh, Scotland, 1997-1998). The long range goal of his research program is to increase reproductive efficiency in cattle. He and his graduate students are working toward a better understanding of the mechanisms regulating ovarian follicular maturation, ovulation, corpus luteum function, and the establishment/maintenance of pregnancy in cattle. He also works closely with Dr. Dave Patterson (State Beef Cattle Reproduction Specialist) on the development of economical and effective methods for timed insemination in beef heifers and cows.

Professional Experience



1980-1986: Assistant Professor, Animal Sciences Department, University of Missouri.

1986-1987: Associate Professor, Animal Sciences Department, University of Missouri.

1987-1988: Visiting Scientist, Department of Molecular Embryology, AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, United Kingdom.

1988-1990: Associate Professor, Animal Sciences Department, University of Missouri.

1996-1997: Visiting Scientist, Department of Development and Reproduction, Roslin Institute (Edinburgh), Roslin, Midlothian, United Kingdom.

1990-2001: Professor, Animal Sciences Department, University of Missouri.

2001-2006: Interim Director, Division of Animal Sciences, University of Missouri.

2006-Present Professor, Division of Animal Sciences, University of Missouri.

Awards and Honors



Midwest Section American Society of Animal Science Young Animal Scientist Research Award, 1991.

College of Agriculture Undergraduate Teaching Award, 1993.

William T. Kemper Fellowship for Teaching Excellence – 1995.

CAFNR Outstanding Researcher Award - 2003.

Frederick B. Mumford Outstanding Faculty Award - 2004.

Society for the Study of Reproduction Trainee Mentoring Award, 2008.

American Society of Animal Science Distinguished Teaching Award, 2008.

American Society of Animal Science Physiology and Endocrinology Award, 2009.

Mizzou Alumni Association Distinguished Faculty Award, 2009.

USDA Regional Teaching Award, 2010.

Governor’s Teaching Award, 2013.

Teaching Physiology



There is a profound difference between being a student in an animal science course and being an animal scientist! An animal science student is frequently a passive observer in the classroom or laboratory; whereas, an animal scientist is a practitioner of the discipline. It is one thing to memorize information but quite another to gain insight into a problem or make an intelligent decision. Becoming an animal scientist is an active process of assimilating and integrating information to make a decision or solve a problem. To be an animal scientist, you need to think like an animal scientist and do the things that animal scientists do. My goal is to assist students in becoming animal scientists and I have designed the following courses to help accomplish this goal.

Courses



AnSc 4314 - Physiology of Reproduction (course webpage)

AnSc 4384 - Reproductive Management (course webpage)

AnSc 9434 - Neuroendocrine and Gonadal Function.

Research Interests



My research program is focused on mechanisms associated with follicular development culminating in the release of a fertilizable germ cell and formation of a corpus luteum. The goal of my research program is to better understand extraovarian and intraovarian mechanisms regulating follicular maturation, oocyte competence, corpus luteum function, and the establishment and maintenance of pregnancy in beef cattle. More specifically, we are investigating physiological, cellular, and molecular factors involved in ovulation of a fully competent oocyte, and development of a maternal environment conducive to pregnancy success. A deeper understanding of the preceding mechanisms should result in the development of improved methods of controlling the time of ovulation and increasing the pregnancy rate to a single insemination.

Publications (last five years)



Perry, G.A., M.F. Smith, A.J. Roberts, M.D. MacNeil, and T.W. Geary. 2007. Relationship between size of ovulatory follicle and pregnancy success in beef heifers. J. Anim. Sci 85:684-689.

Schafer, D.J., J.F. Bader, J.P. Meyer, J.K. Haden, M.R. Ellersieck, M.C. Lucy, M.F. Smith, and D.J. Patterson. 2007. Comparison of progestin-based protocols to synchronize estrus and ovulation before fixed-time artificial insemination in postpartum beef cows. J. Anim Sci 85:1940-1945.

Busch, D.C., D. J. Wilson, D. J. Schafer, N. R. Leitman, J. K. Haden, M. R. Ellersieck, M.F. Smith, and D. J. Patterson. 2007. Comparison of progestin-based estrus synchronization protocols before fixed-time artificial insemination on pregnancy rate in beef heifers. J Anim Sci 85: 1933-1939.

Atkins, J.A., D. C. Busch, J. F. Bader, D. H. Keisler, D. J. Patterson, M. C. Lucy, and M.F. Smith. 2008. Gonadotropin-releasing hormone-induced ovulation and luteinizing hormone release in beef heifers: Effect of day of the cycle. J Anim Sci 86: 83-93.

Busch, D.C., J. A. Atkins, J. F. Bader, D. J. Schafer, D. J. Patterson, T. W. Geary, and M.F. Smith. 2008. Effect of ovulatory follicle size and expression of estrus on progesterone secretion in beef cows. J Anim Sci 86:553-563.

Leitman, N.R., D.C. Busch, J.F. Bader, D.A. Mallory, D.J. Wilson, M.C. Lucy, M.R. Ellersieck, M.F. Smith, and D.J. Patterson. 2008. Comparison of protocols to synchronize estrus and ovulation in estrous-cycling and prepubertal beef heifers. J. Anim Sci 86:1808-1818.

Busch, D.C., D.J. Schafer, D.J. Wilson, D.A. Mallory, N.R. Leitman, J.K. Haden, M.R. Ellersieck, M.F. Smith and D.J. Patterson. 2008. Timing of artificial insemination in postpartum beef cows following administration of the CO-Synch + controlled internal drug-release protocol. J. Anim Sci 86:1519-1525.

Leitman, N.R., D.C. Busch, D.A. Mallory, D.J. Wilson, M.R. Ellersieck, M.F. Smith, and D.J. Patterson. 2009. Comparison of long-term CIDR-based protocols to synchronize estrus in beef heifers. Anim Repro Sci 114:345-355.

Leitman, N.R., D.C. Busch, D.J. Wilson, D.A. Mallory, M.R. Ellersieck, M.F. Smith, and D.J. Patterson. 2009. Comparison of controlled internal drug release insert-based protocols to synchronize estrus in prepubertal and estrous cycling beef heifers. J. Anim Sci. 87:3976-3982.

Garverick, H.A., J.L. Juengel, P. Smith, D.A. Heath, M.N. Burkhart, G.A. Perry, M.F. Smith, and K.P. McNatty. 2009. Development of the ovary and ontogeny of mRNA and protein for P450 aromatase (arom) and estrogen receptors (ER) alpha and Beta during early fetal life in cattle. Anim. Reprod. Sci 117:24-33.

Burkhart, M.N., J.L. Juengel, P.R. Smith, D.A. Heath, G.A. Perry, M.F. Smith and H.A. Garverick. 2010. Morphological development characterization of aromatase and estrogen receptors alpha and beta in fetal ovaries of cattle from days 110 to 250. Anim. Reprod. Sci. 117:43-54.

Mallory, D.A., J. Wilson, D.C. Busch, M.R. Ellersieck, M.F. Smith, and D.J. Patterson. 2010. Comparison of long-term progestin-based estrus synchronization protocols in beef heifers. J Anim Sci 88:3568-3578.

Atkins, J.A., M.F. Smith, K.J. Wells and T.W. Geary. 2010. Factors affecting preovulatory follicle diameter and ovulation rate after gonadotropin-releasing hormone in postpartum beef cows. Part I: Cycling Cows. J Anim Sci 88:2300-2310.

Atkins, J.A., M.F. Smith, K.J. Wells and T.W. Geary. 2010. Factors affecting preovulatory follicle diameter and ovulation rate after gonadotropin-releasing hormone in postpartum beef cows. Part II: Anestrous Cow. J Anim Sci 88:2311-2320.

D.J. Wilson, D.A. Mallory, D.C. Busch, N.R. Leitman, J.K. Haden, D.J. Schafer, M.R. Ellersieck, M.F. Smith and D.J. Patterson. 2010. Comparison of short-term progestin-based protocols to synchronize estrus and ovulation in postpartum beef cows. J Anim Sci 88:2045-2054.

J. Franken, J. Parcell, D. Patterson, M.F. Smith, and S. Poock. 2010. Cow-calf producer interest in retained ownership. J of Agribusiness 28(1)49-59.

Mallory, D.A., D.J. Wilson, D.C. Busch, M.R. Ellersieck, M.F. Smith, and D.J. Patterson. 2010. Comparison of long-term progestin-based estrus synchronization protocols in beef heifers. J. Anim. Sci. 88:3568-3578.

Mallory, D.A., J. M. Nash, M.R. Ellersieck, M.F. Smith, and D.J. Patterson. 2011. Comparison of long-term progestin-based protocols to synchronize estrus before fixed-time artificial insemination in beef heifers. J. Anim. Sci. 89:1358-1365.

Nash, J.M., D. A. Mallory, M.R. Ellersieck, S.E. Poock, M.F. Smith, and D. J. Patterson. 2012. Comparison of long- verses short-term CIDR-based protocols to synchronize estrus prior to fixed-time AI in postpartum beef cows. Anim. Reprod. Sci. 132: 11-16.

Pohler, K.G., T.W. Geary, J. A. Atkins, G. A. Perry, E. M. Jinks, and M.F. Smith, 2012, Follicular Determinants of Pregnancy Establishment and Maintenance, Cell and Tissue Research 349: 649-664.

Atkins, J.A., M.F. Smith, M. D. MacNeil, E. M. Jinks, F. M. Abreu, L. J. Alexander, and T. W. Geary, 2013, Pregnancy establishment and maintenance in cattle, J. Anima. Sci. 91: 722-733.

Jinks, E. M., M.F. Smith, J. A. Atkins, K. G. Pohler, G. A. Perry, M. D. MacNeil, A. J. Roberts, R. C. Waterman and T. W. Geary, 2013, Preovulatory estradiol and the establishment and maintenance of pregnancy in suckled beef cows, J. Anim. Sci. 91: 1176-1185.

Geary, T.W., M.F. Smith, M. D. MacNeil, M. L. Day, G. A. Bridges, G. A. Perry, F. M. Abreu, J. A. Atkins, K. G. Pohler, E. M. Jinks, and C. A. Madsen. 2013. Influence of Follicular Characteristics at Ovulation on Early Embryo Survival. J. Anim. Sci 91:3014-3021.