When
chromosomes duplicate by DNA replication, each duplicated chromosome is
referred to as a chromatid. This is a diagram of a replicated chromosome.
These identical copies of the DNA molecule are held together at the centromere
region. Some of the microtubules of a dividing cell connect to the replicated
chromatids at this region. Telomeres are of increasing interest in the
biotech community. These telomeres are specific nucleotide sequences that
don't contain coding DNA sequences but contain multiple repeats of short
nucleoide sequences. Six bases might be repeated 100 to 1000 times in
these telomeric regions. These regions seem to protect our actual coding
genes from being eroded through time. It is of interest that telomeres
have been implicated as one of the factors in the life span of an organism
or tissue type. Certainly, much work is continuing with telomeres in aging
and cancer studies.
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